Tucked on a quiet street in the sophisticated Recoleta neighborhood, the upscale Serena Hotel offers a polished, boutique environment. The property can give an exclusive, almost restrictive first impression, with a front door that requires a key to enter and its adults only policy. But the chic streamline interiors, holistic spa treatments, and heated pool foster an air of serenity and intimacy. Its 34 rooms are tastefully decorated and outfitted with LCD TVs and minibars. For accommodation amidst a younger demographic and a more touristy vibe, travelers might prefer the funky Aspen Square hotel in the Palermo neighborhood, which also happens to be kid-friendly.

The 83-room upper-middle-range Lafayette Hotel is located in Microcentro, close to just about everything: shopping hubs, museums, the financial district, and Puerto Madero’s revitalized waterfront. In fact, once guests step out of the hotel lobby -- a bright, large and welcoming area with plenty of seating -- and onto Reconquista Street, they are right in the thick of the city’s bustle. The rooms are generously sized (suites and family rooms are available), but the windows don't let in a lot of natural light and some overlook unattractive alleys. The hotel's Midi restaurant serves up international cuisine, and a better-than-average free breakfast is offered daily. No pool here, but there is a spa. For location, price, and sizable rooms, this is a good choice for those wanting to be in the middle of the action.